Effect on mood of subthalamic DBS for Parkinson's disease - A consecutive series of 24 patients

被引:215
作者
Berney, A
Vingerhoets, F
Perrin, A
Phil, L
Guex, P
Villemure, JG
Burkhard, PR
Benkelfat, C
Ghika, J
机构
[1] McGill Univ, Neurobiol Psychiat Unit, Montreal, PQ H3A 1A1, Canada
[2] CHU Vaudois, Dept Psychiat, CH-1011 Lausanne, Switzerland
[3] CHU Vaudois, Dept Neurol, CH-1011 Lausanne, Switzerland
[4] CHU Vaudois, Dept Neurosurg, CH-1011 Lausanne, Switzerland
[5] HUG, Dept Neurol, Geneva, Switzerland
关键词
D O I
10.1212/01.WNL.0000032756.14298.18
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A series of 24 consecutive PD patients were prospectively studied prior to and within 6 months postoperatively for mood, motor, and cognitive status to investigate the effects on mood of subthalamic deep brain stimulation (DBS) in PD. In six patients (25%), mood state worsened significantly, and three were transiently suicidal despite clear motor improvement. Caregivers and patients should be educated about the potential impact of this neurosurgical procedure on mood.
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页码:1427 / 1429
页数:3
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