Steroidal ureas as enantioselective receptors for an N-acetyl α-amino carboxylate

被引：49

作者：

Siracusa, L

Hurley, FM

Dresen, S

Lawless, LJ

Pérez-Payán, MN

Davis, AP

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

[2] Univ Dublin Trinity Coll, Dept Chem, Dublin 2, Ireland

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 26期

关键词：

D O I：

10.1021/ol027009l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cholic acid has been elaborated into three regioisomeric bis-carbamoylureas, which have been investigated as enantioselective receptors for N-acetyl phenylalanine. L/D selectivities, peaking at 5:1, have been determined by a sensitive and rapid MS-based extraction method that should be generalizable to related systems.

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页码：4639 / 4642

页数：4

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