Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma

被引:286
作者
Lee, Jae-Hyun
Jun, Young-Wook
Yeon, Soo-In
Shin, Jeon-Soo [1 ]
Cheon, Jinwoo
机构
[1] Yonsei Univ, Coll Med, Dept Microbiol, Seoul 120752, South Korea
[2] Yonsei Univ, Dept Chem, Seoul 120749, South Korea
关键词
colloids; diagnostic agents; hybrid materials; nanotechnology; NMR imaging;
D O I
10.1002/anie.200603052
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Working together: A core-satellite" hybrid nanoparticle probe provides highly improved fluorescence and magnetic resonance (MR) imaging capabilities through synergistic enhancement of its respective components. These hybrid nanoprobes can be used for dual-modal fluorescence and MR imaging of neuroblastoma with expressed polysialic acids. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA."
引用
收藏
页码:8160 / 8162
页数:3
相关论文
共 28 条
[1]   The use of nanocrystals in biological detection [J].
Alivisatos, P .
NATURE BIOTECHNOLOGY, 2004, 22 (01) :47-52
[2]   MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles [J].
Artemov, D ;
Mori, N ;
Okollie, B ;
Bhujwalla, ZM .
MAGNETIC RESONANCE IN MEDICINE, 2003, 49 (03) :403-408
[3]   Controlled clustering of superparamagnetic nanoparticles using block copolymers: Design of new contrast agents for magnetic resonance imaging [J].
Berret, JF ;
Schonbeck, N ;
Gazeau, F ;
El Kharrat, D ;
Sandre, O ;
Vacher, A ;
Airiau, M .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (05) :1755-1761
[4]  
Bharali DJ, 2005, P NATL ACAD SCI USA, V102, P11539, DOI 10.1073/pnas.0504926102
[5]   In vitro cytotoxicity of oxide nanoparticles: Comparison to asbestos, silica, and the effect of particle solubility [J].
Brunner, Tobias J. ;
Wick, Peter ;
Manser, Pius ;
Spohn, Philipp ;
Grass, Robert N. ;
Limbach, Ludwig K. ;
Bruinink, Arie ;
Stark, Wendelin J. .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2006, 40 (14) :4374-4381
[6]   A nude mice model of human rhabdomyosarcoma lung metastases for evaluating the role of polysialic acids in the metastatic process [J].
Daniel, L ;
Durbec, P ;
Gautherot, E ;
Rouvier, E ;
Rougon, G ;
Figarella-Branger, D .
ONCOGENE, 2001, 20 (08) :997-1004
[7]   Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles [J].
Elghanian, R ;
Storhoff, JJ ;
Mucic, RC ;
Letsinger, RL ;
Mirkin, CA .
SCIENCE, 1997, 277 (5329) :1078-1081
[8]  
FIGARELLABRANGER DF, 1990, CANCER RES, V50, P6364
[9]  
Fukuda M, 1996, CANCER RES, V56, P2237
[10]   In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals [J].
Huh, YM ;
Jun, YW ;
Song, HT ;
Kim, S ;
Choi, JS ;
Lee, JH ;
Yoon, S ;
Kim, KS ;
Shin, JS ;
Suh, JS ;
Cheon, J .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (35) :12387-12391