Context Although the prevalence of obesity has markedly increased among US adults, health risks vary according to the severity of obesity. Persons with class 3 obesity (body mass index [BMI] greater than or equal to 40) are at greatest risk, but there is little information about this subgroup. Objective To examine correlates of class 3 obesity and secular trends. Design, Setting, and Participants Adults (aged greater than or equal to 18 years) in the United States who participated in the Behavioral Risk Factor Surveillance System telephone survey between 1990 (75600 persons) and 2000 (164250 persons). Main Outcome Measure Body mass index calculated from self-reported weight and height. Results The prevalence of class 3 obesity increased from 0.78% (1990) to 2.2% (2000). In 2000, class 3 obesity was highest among black women (6.0%), persons who had not completed high school (3.4%), and persons who are short. During the 11-year period, the median BMI level increased by 1.2 units and the 95th percentile increased by 3.2 units. Conclusion The prevalence of class 3 obesity is increasing rapidly among adults. Because these extreme BMI levels are associated with the most severe. health complications, the incidence of various diseases will increase substantially in the future.