Language development and fragile X syndrome: Profiles, syndrome-specificity, and within-syndrome differences

被引:134
作者
Abbeduto, Leonard
Brady, Nancy
Kover, Sara T.
机构
[1] Univ Wisconsin, Waisman Ctr, Madison, WI 53705 USA
[2] Univ Kansas, Schiefelbusch Inst Life Span Studies, Lawrence, KS 66045 USA
来源
MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS | 2007年 / 13卷 / 01期
关键词
fragile X syndrome; language; communication; autism; mental retardation;
D O I
10.1002/mrdd.20142
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Fragile X syndrome (FXS) is the leading inherited cause of mental retardation. In this article, we review what is known about the language and related problems of individuals with FXS. In doing so, we focus on the syndrome-specific features of the language phenotype and on the organismic (i.e., genetic and individual neurocognitive and behavioral) and environmental factors associated with within-syndrome variation in the phenotype. We also briefly review those aspects of the behavioral phenotype of FXS that are relevant for understanding syndrome-specific features of, and within-syndrome variability in, language. The review includes summaries of research on the pre-linguistic foundations for language development and on each of the major components of language (i.e., vocabulary, morphosyntax, and pragmatics). Throughout the review, we point out implications of existing research for intervention as well as directions for future research. (C) 2007 Wiley-Liss, Inc. MRDD Research Reviews 2007,13:36-46.
引用
收藏
页码:36 / 46
页数:11
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