Liquid chromatography-atmospheric pressure chemical ionization mass spectrometry as a tool for the characterization of anthraquinone derivatives from Chinese herbal medicine

被引：16

作者：

Li, WK

Chan, CL

Lueng, HW

机构：

[1] Hong Kong Baptist Univ, Dept Chem, Kowloon, Hong Kong, Peoples R China

[2] Hong Kong Baptist Univ, Inst Advancement Chinese Med, Kowloon, Hong Kong, Peoples R China

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 2000年 / 52卷 / 06期

关键词：

D O I：

10.1211/0022357001774408

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

We have examined the anthraquinone derivatives of a Chinese herb medicine 'Rhubarb' by using HPLC/MS/MS, equipped with an atmospheric pressure chemical ionization source. The simultaneous determination of five ingredients in the sample extracts by HPLC/MS/MS was demonstrated. Product ion spectra of these components in the extracts were obtained and matched against known standards. Concentrations of these active ingredients were estimated by multiple reaction monitoring in the negative ion mode using a single HPLC run.

引用

页码：723 / 729

页数：7

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