Interstitial pneumonitis associated with infliximab therapy without methotrexate treatment

被引：27

作者：

Taki, Hirofumi ^{[1
]}

Kawagishi, Yukio ^{[1
]}

Shinoda, Koichiro ^{[1
]}

Hounoki, Hiroyuki ^{[1
]}

Ogawa, Reina ^{[1
]}

Sugiyama, Eiji ^{[1
]}

Tobe, Kazuyuki ^{[1
]}

机构：

[1] Toyama Univ, Dept Internal Med 1, Toyama 9300194, Japan

来源：

RHEUMATOLOGY INTERNATIONAL | 2009年 / 30卷 / 02期

关键词：

RHEUMATOID-ARTHRITIS; DISEASE;

D O I：

10.1007/s00296-009-0931-6

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Tumor necrosis factor (TNF)-alpha inhibitors are increasingly being used to treat rheumatoid arthritis. Infliximab (INF) is a TNF-alpha inhibitor that is usually used in combination with methotrexate (MTX). Interstitial lung disease (ILD) during combination therapy has been attributed to MTX rather than INF. However, INF-associated ILD without combination with MTX has recently been reported. We describe herein a case of severe ILD secondary to INF without MTX therapy.

引用

页码：275 / 276

页数：2

共 10 条

[1]

Infliximab treatment in a patient with rheumatoid arthritis and pulmonary fibrosis [J].