A direct catalytic asymmetric Mannich-type reaction to syn-amino alcohols

被引：336

作者：

Trost, BM ^{[1
]}

Terrell, LR ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 02期

关键词：

D O I：

10.1021/ja028782e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Mannich reaction is one of the most widely utilized chemical transformations for the construction of nitrogen-containing compounds. With the increasing occurrence of nitrogen in drugs and natural products, highly asymmetric variants of the Mannich reaction are desirable. In this communication, we report the application of our dinuclear zinc catalyst to a highly asymmetric Mannich-type reaction to generate syn 1, 2-amino alcohols. Copyright © 2003 American Chemical Society.

引用

页码：338 / 339

页数：2

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