Dose-dependent immune response to Mycobacterium bovis BCG vaccination in neonates

被引：10

作者：

Davids, Virginia

Hanekom, Willem

Gelderbloem, Sebastian J.

Hawkridge, Anthony

Hussey, Gregory

Sheperd, Ronel

Workman, Lesley

Soler, Jorge

Murray, Rose Ann

Ress, Stanley R.

Kaplan, Gilla

机构：

[1] Univ Med & Dent New Jersey, Publ Hlth Res Inst, Lab Mycobacterial Immun & Pathogenesis, Newark, NJ 07103 USA

[2] Univ Cape Town, Inst Infect Dis & Mol Med, S Africa TB Vaccine Initiat, Cape Town, South Africa

[3] Univ Cape Town, Groote Schuur Hosp, Dept Med, Div Clin Immunol, ZA-7925 Cape Town, South Africa

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2007年 / 14卷 / 02期

关键词：

D O I：

10.1128/CVI.00309-06

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 10-week-old infants vaccinated at birth with Japanese Mycobacterium bovis BCG, the number of dermal needle penetrations correlated positively with frequency of proliferating CD4(+) T cells in whole blood following BCG stimulation for 6 days but did not correlate with secreted cytokine levels after 7 It or interferon CD4(+) T-cell frequency after 12 h of BCG stimulation.

引用

页码：198 / 200

页数：3

共 24 条

[1] CYTOKINE PRODUCTION AT THE SITE OF DISEASE IN HUMAN TUBERCULOSIS [J].

BARNES, PF ;

LU, SZ ;

ABRAMS, JS ;

WANG, E ;

YAMAMURA, M ;

MODLIN, RL .

INFECTION AND IMMUNITY, 1993, 61 (08) :3482-3489

[2] A historical and molecular phylogeny of BCG strains [J].

Behr, MA ;

Small, PM .

VACCINE, 1999, 17 (7-8) :915-922

[3]

Caruso AM, 1999, J IMMUNOL, V162, P5407

[4] Genetic dissection of immunity to mycobacteria: The human model [J].

Casanova, JL ;

Abel, L .

ANNUAL REVIEW OF IMMUNOLOGY, 2002, 20 :581-620

[5] Mycobacterium bovis BCG substrains confer different levels of protection against Mycobacterium tuberculosis infection in a BALB/c model of progressive pulmonary tuberculosis [J].

Castillo-Rodal, AI ;

Castañón-Arreola, M ;

Hernández-Pando, R ;

Calva, JJ ;

Sada-Díaz, E ;

López-Vidal, Y .

INFECTION AND IMMUNITY, 2006, 74 (03) :1718-1724

[6] Gamma interferon-producing CD4+ T lymphocytes in the lung correlate with resistance to infection with Mycobacterium tuberculosis [J].

Chackerian, AA ;

Perera, TV ;

Behar, SM .

INFECTION AND IMMUNITY, 2001, 69 (04) :2666-2674

[7] Single intranasal mucosal Mycobactetium bovis BCG vaccination confers improved protection compared to subcutaneous vaccination against pulmonary tuberculosis [J].

Chen, LH ;

Wang, J ;

Zganiacz, A ;

Xing, Z .

INFECTION AND IMMUNITY, 2004, 72 (01) :238-246

[8]

Corbel M J, 2004, Vaccine, V22, P2675, DOI 10.1016/j.vaccine.2004.01.050

[9] The effect of bacille Calmette-Guerin vaccine strain and route of administration on induced immune responses in vaccinated infants [J].

Davids, V ;

Hanekom, WA ;

Mansoor, N ;

Gamieldien, H ;

Gelderbloem, SJ ;

Hawkridge, A ;

Hussey, GD ;

Hughes, EJ ;

Soler, J ;

Murray, RA ;

Ress, SR ;

Kaplan, G .

JOURNAL OF INFECTIOUS DISEASES, 2006, 193 (04) :531-536

[10] Inherited disorders of IL-12-and IFNγ-mediated immunity:: a molecular genetics update [J].

Döffinger, R ;

Dupuis, S ;

Picard, C ;

Fieschi, C ;

Feinberg, J ;

Barcenas-Morales, G ;

Casanova, JL .

MOLECULAR IMMUNOLOGY, 2002, 38 (12-13) :903-909

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