The study of cell-death proteins in the outer mitochondrial membrane by chemical cross-linking

被引：8

作者：

Ali, ST ^{[1
]}

Coggins, JR ^{[1
]}

Jacobs, HT ^{[1
]}

机构：

[1] UNIV GLASGOW,INST BIOMED & LIFE SCI,DIV MOL GENET,GLASGOW G12 8QQ,LANARK,SCOTLAND

来源：

BIOCHEMICAL JOURNAL | 1997年 / 325卷

关键词：

D O I：

10.1042/bj3250321

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chemical cross-linking was used to study the interactions of the anti-cell-death protein Bcl2 with other proteins in the outer mitochondrial membrane. cross-linking of mitochondrial surface proteins produced a large Bcl2-containing complex (>200 kDa), and a Bcl2-derived peptide was shown to cross-link specifically with a mitochondrial protein identified by immunoblotting as Raf-1 kinase.

引用

页码：321 / 324

页数：4

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