Characterization of the tetracycline resistance plasmid pMD5057 from Lactobacillus plantarum 5057 reveals a composite structure

被引：103

作者：

Danielsen, M ^{[1
]}

机构：

[1] Chr Hansen AS, Identificat Sect, Appl Biotechnol, DK-2970 Horsholm, Denmark

来源：

PLASMID | 2002年 / 48卷 / 02期

关键词：

Lactobacillus plantarum; tetracycline resistance plasmid; composite structure;

D O I：

10.1016/S0147-619X(02)00118-X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The 10,877bp tetracycline resistance plasmid pMD5057 from Lactobacillus plantarion 5057 was completely sequenced. The sequence revealed a composite structure containing DNA from up to four different sources. The replication region had homology to other plasmids of lactic acid bacteria while the tetracycline resistance region, containing a tet(M) gene, had high homology to sequences from clostridium perfringens and Staphylococcus aureus. Within the tetracycline resistance region it Lactobacillus IS-element was found. The remaining part of the plasmid contained three open reading, fratries with unknown functions. The composite structure with several truncated genes suggests a recent assembly of the plasmid. This is the first sequence of an antibiotic resistance plasinid isolated from L. phantarum. (C) 2002 Elsevier Science (USA). All rights reserved.

引用

页码：98 / 103

页数：6

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