Helicobacter species ribosomal DNA recovered from the liver tissue of Chinese patients with primary hepatocellular carcinoma

被引:29
作者
Fan, XG [1 ]
Peng, XN
Huang, Y
Yakoob, J
Wang, ZM
Chen, YP
机构
[1] Cent S Univ, Xiangya Hosp, Dept Infect Dis, Changsha 410008, Peoples R China
[2] Cent S Univ, Xiangya Hosp, Dept Surg, Changsha 410008, Peoples R China
[3] Cent S Univ, Xiangya Hosp, Dept Pathol, Changsha 410008, Peoples R China
关键词
D O I
10.1086/344770
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Using polymerase chain reaction (PCR), we examined 16S ribosomal DNA (rDNA) of Helicobacter species in liver tissue specimens obtained from 15 patients with hepatocellular carcinoma. Sixty percent (9 of 15) of these specimens were found to be positive for Helicobacter species. Four 16S rDNA fragments from positive PCR samples were directly sequenced. By sequence comparison, all were found to be 99% identical to the 16S rRNA of Helicobacter pylori.
引用
收藏
页码:1555 / 1557
页数:3
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