TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p

被引：66

作者：

Jasek, M. ^{[1
]}

Gondek, L. P. ^{[1
]}

Bejanyan, N. ^{[1
]}

Tiu, R. ^{[1
]}

Huh, J. ^{[1
,2
]}

Theil, K. S. ^{[3
]}

O'Keefe, C. ^{[1
]}

McDevitt, M. A. ^{[4
,5
,6
]}

Maciejewski, J. P. ^{[1
,7
]}

机构：

[1] Cleveland Clin, Dept Translat Hematol & Oncol Res, Taussig Canc Inst, Cleveland, OH 44106 USA

[2] Ewha Womans Univ, Sch Med, Dept Lab Med, Seoul, South Korea

[3] Cleveland Clin, Dept Clin Pathol, Cleveland, OH 44106 USA

[4] Johns Hopkins Univ, Sch Med, Div Hematol, Baltimore, MD USA

[5] Johns Hopkins Univ, Sch Med, Div Hematol Malignancy, Dept Med, Baltimore, MD USA

[6] Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA

[7] Cleveland Clin, Taussig Canc Inst, Dept Hematol Oncol & Blood Disorders, Cleveland, OH 44106 USA

来源：

LEUKEMIA | 2010年 / 24卷 / 01期

关键词：

COMPLEX KARYOTYPE; POOR-PROGNOSIS; LEUKEMIA; P53; GENE;

D O I：

10.1038/leu.2009.189

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：216 / 219

页数：4

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