Ticagrelor - Is There Need for a New Player in the Antiplatelet-Therapy Field?

被引:99
作者
Schoemig, Albert [1 ,2 ]
机构
[1] Deutsch Herzzentrum Munich, Dept Cardiol, Munich, Germany
[2] First Med Klin Rechts Isar, Munich, Germany
关键词
PLATELET INHIBITION; CLOPIDOGREL; PRASUGREL; POLYMORPHISMS; ASPIRIN;
D O I
10.1056/NEJMe0906549
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1108 / 1111
页数:4
相关论文
共 10 条
[1]  
[Anonymous], N ENGL J MED
[2]   Intensifying platelet inhibition - Navigating between scylla and charybdis [J].
Bhatt, Deepak L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (20) :2078-2081
[3]   Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin [J].
Gilard, Martine ;
Arnaud, Bertrand ;
Cornily, Jean-Christophe ;
Le Gal, Gregoire ;
Lacut, Karine ;
Le Calvez, Genevive ;
Mansourati, Jacques ;
Mottier, Dominique ;
Abgrall, Jean-Francois ;
Boschat, Jacques .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 51 (03) :256-260
[4]   Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel Relationship to Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes [J].
Mega, Jessica L. ;
Close, Sandra L. ;
Wiviott, Stephen D. ;
Shen, Lei ;
Hockett, Richard D. ;
Brandt, John T. ;
Walker, Joseph R. ;
Antman, Elliott M. ;
Macias, William L. ;
Braunwald, Eugene ;
Sabatine, Marc S. .
CIRCULATION, 2009, 119 (19) :2553-U44
[5]   Cytochrome P-450 Polymorphisms and Response to Clopidogrel. [J].
Mega, Jessica L. ;
Close, Sandra L. ;
Wiviott, Stephen D. ;
Shen, Lei ;
Hockett, Richard D. ;
Brandt, John T. ;
Walker, Joseph R. ;
Antman, Elliott M. ;
Macias, William ;
Braunwald, Eugene ;
Sabatine, Marc S. .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (04) :354-362
[6]   Platelet Reactivity After Clopidogrel Treatment Assessed With Point-of-Care Analysis and Early Drug-Eluting Stent Thrombosis [J].
Sibbing, Dirk ;
Braun, Siegmund ;
Morath, Tanja ;
Mehilli, Julinda ;
Vogt, Wolfgang ;
Schoemig, Albert ;
Kastrati, Adnan ;
von Beckerath, Nicolas .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (10) :849-856
[7]   Prasugrel achieves greater and faster P2Y12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease [J].
Wallentin, Lars ;
Varenhorst, Christoph ;
James, Stefan ;
Erlinge, David ;
Braun, Oscar Oe ;
Jakubowski, Joseph A. ;
Sugidachi, Atsuhiro ;
Winters, Kenneth J. ;
Siegbahn, Agneta .
EUROPEAN HEART JOURNAL, 2008, 29 (01) :21-30
[8]   Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes [J].
Wallentin, Lars ;
Becker, Richard C. ;
Budaj, Andrzej ;
Cannon, Christopher P. ;
Emanuelsson, Hakan ;
Held, Claes ;
Horrow, Jay ;
Husted, Steen ;
James, Stefan ;
Katus, Hugo ;
Mahaffey, Kenneth W. ;
Scirica, Benjamin M. ;
Skene, Allan ;
Steg, Philippe Gabriel ;
Storey, Robert F. ;
Harrington, Robert A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (11) :1045-1057
[9]   Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention - The prasugrel in comparison to clopidogrel for inhibition of platelet activation and aggregation-thrombolysis in myocardial infarction 44 trial [J].
Wiviott, Stephen D. ;
Trenk, Dietmar ;
Frelinger, Andrew L. ;
O'Donoghue, Michelle ;
Neumann, Franz-Josef ;
Michelson, Alan D. ;
Angiolillo, Dominick J. ;
Hod, Hanoch ;
Montalescot, Gilles ;
Miller, Debra L. ;
Jakubowski, Joseph A. ;
Cairns, Richard ;
Murphy, Sabina A. ;
McCabe, Carolyn H. ;
Antman, Elliott M. ;
Braunwald, Eugene .
CIRCULATION, 2007, 116 (25) :2923-2932
[10]   Prasugrel versus clopidogrel in patients with acute coronary syndromes [J].
Wiviott, Stephen D. ;
Braunwald, Eugene ;
McCabe, Carolyn H. ;
Montalescot, Gilles ;
Ruzyllo, Witold ;
Gottlieb, Shmuel ;
Neumann, Franz-Joseph ;
Ardissino, Diego ;
De Servi, Stefano ;
Murphy, Sabina A. ;
Riesmeyer, Jeffrey ;
Weerakkody, Govinda ;
Gibson, C. Michael ;
Antman, Elliott M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (20) :2001-2015