Green tea and cancer prevention

被引：24

作者：

Fujiki, H

Suganuma, M

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Dept Biochem, Tokushima 7708514, Japan

[2] Saitama Canc Ctr, Ina, Saitama 3620806, Japan

来源：

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES | 2002年 / 78卷 / 09期

关键词：

EGCG; tumor promotion; tea polyphenols; synergistic effects;

D O I：

10.2183/pjab.78.263

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We found that (-)-epigallocatechin gallate (EGCG), the main constituent of green tea and green tea extract, the lyophitized form of green tea infusion, inhibited both activation of protein kinase C and tumor promotion on mouse skin: The results led us to suggest green tea as a cancer preventive for humans. Inhibition of chemical carcinogenesis in rodents, inhibition of cell growth and induction of apoptosis on human cancer cell lines, organ distribution of H-3-EGCG in mice, multifunctional actions, and the synergistic cancer preventive activity of green tea with sulindac were studied. All our results show that green tea is a promising beverage for, the purpose of cancer prevention in humans.

引用

页码：263 / 270

页数：8

共 41 条

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