Retrospective study of prion-protein accumulation in tonsil and appendix tissues

被引：77

作者：

Ironside, JW ^{[1
]}

Hilton, DA

Ghani, A

Johnston, NJ

Conyers, L

McCardle, LM

Best, D

机构：

[1] Univ Edinburgh, Western Gen Hosp, Natl CJD Surveillance Unit, Edinburgh EH4 2XU, Midlothian, Scotland

[2] Derriford Hosp, Dept Histopathol, Plymouth PL6 8DH, Devon, England

[3] Univ Oxford, Welcome Trust Epidemiol Infect Dis, Oxford OX1 2JD, England

来源：

LANCET | 2000年 / 355卷 / 9216期

关键词：

D O I：

10.1016/S0140-6736(00)02243-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To Identify individuals who could be at high risk of developing vCJD, a sensitive immunohistochemical technique was used to detect prion protein in a retrospective series of over 3000 tonsil and appendix specimens. No positives were detected but further studies are required to help reduce uncertainties about possible future numbers of vCJD cases in the UK.

引用

页码：1693 / 1694

页数：2

共 5 条

[1] Epidemiological determinants of the pattern and magnitude of the vCJD epidemic in Great Britain [J].