Human infection with Ehrlichia canis accompanied by clinical signs in Venezuela

被引:222
作者
Perez, Miriam
Bodor, Mairim
Zhang, Chunbin
Xiong, Qingmin
Rikihisa, Yasuko
机构
[1] Ohio State Univ, Coll Vet Med, Dept Vet Biosci, Columbus, OH 43210 USA
[2] Univ Centroccidental Lisandro Alvarado, Dept Med & Cirugia, Decanato Cienccias Vet, Lara, Venezuela
[3] Hosp Cent Antonio Maria Pineda, Serv Emergencia Adultos, Barquisimeto Ed, Lara, Venezuela
来源
CENTURY OF RICKETTSIOLOGY: EMERGING, REEMERGING RICKETTSIOSES, MOLECULAR DIAGNOSTICS, AND EMERGING VETERINARY RICKETTSIOSES | 2006年 / 1078卷
关键词
16s rRNA; Ehrlichia canis; human; infection; Venezuela;
D O I
10.1196/annals.1374.016
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A total of 20 human patients with clinical signs compatible with human monocytic ehrlichiosis (HME), who were admitted to the emergency clinic in Lara State, Venezuela, were studied. Thirty percent (6/20) patients were positive for Ehrlichia canis 16S rRNA on gene-specific polymerase chain reaction (PCR). Compared with the U.S. strains, 16S rRNA gene sequences from all six patients had the same base mutation as the sequence of the E. canis Venezuelan human Ehrlichia (VHE) strain previously isolated from an asymptornatic human. This study is the first report of E. canis infection of human patients with clinical signs of HME.
引用
收藏
页码:110 / 117
页数:8
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