Chondroitin sulfate proteoglycans as mediators of axon growth and pathfinding

被引：165

作者：

Margolis, RU ^{[1
]}

Margolis, RK ^{[1
]}

机构：

[1] SUNY HLTH SCI CTR,DEPT PHARMACOL,BROOKLYN,NY 11203

来源：

CELL AND TISSUE RESEARCH | 1997年 / 290卷 / 02期

关键词：

neurocan; phosphacan; neural cell adhesion molecules; oligosaccharides; tenascin-C;

D O I：

10.1007/s004410050939

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

This review focuses primarily on studies concerning the potential roles of two nervous-tissue-specific chondroitin sulfate proteoglycans, viz., neurocan and phosphacan, in cell interactions and neurite growth in the developing central nervous system. The multiple ligands of these proteoglycans and the modulatory effects of various types of glycosylation are also considered. Other chondroitin sulfate proteoglycans, such as NG2, DSD-1, Cat-301, versican, and biglycan, are briefly discussed in relation to the functional properties that have been ascribed to them.

引用

页码：343 / 348

页数：6

共 47 条

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