Defining the Components of the Research Pipeline

被引：15

作者：

Kleinman, Michael S. ^{[2
]}

Mold, James W. ^{[1
]}

机构：

[1] Univ Oklahoma, Hlth Sci Ctr, Dept Family & Prevent Med, Oklahoma City, OK USA

[2] Univ Oklahoma, Hlth Sci Ctr, Coll Med, Oklahoma City, OK 73190 USA

来源：

CTS-CLINICAL AND TRANSLATIONAL SCIENCE | 2009年 / 2卷 / 04期

关键词：

translational research; human research; practice- and community-based research; translation;

D O I：

10.1111/j.1752-8062.2009.00119.x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The National Institutes of Health (NIH) has proposed that research moves from "bench to bedside" through a Pipeline consisting of distinct research categories bridged by bidirectional translation. The original NIH Pipeline has now been expanded to include practice- and community-based research. We developed operational definitions for the elements along the expanded NIH Pipeline. The proposed definitions were pilot-tested and refined using the Computer Retrieval of Information on Scientific Projects (CRISP) and the Secure Internet-Linked Web Technologies (SILK) database containing funding information for individual NIH awards. Using our definitions, two reviewers independently agreed on the categorization of 94% of 866 National Heart, Lung, and Blood Institute (NHLBI)-funded projects, and 99% of projects could be placed into a single research category.

引用

页码：312 / 314

页数：3