Effects of a Lactobacillus casei 393 fermented milk product on bone metabolism in ovariectomised rats

被引：55

作者：

Kim, Jong Gun ^{[2
]}

Lee, Eungsuk ^{[3
]}

Kim, Sae Hun ^{[3
]}

Whang, Kwang Youn ^{[2
]}

Oh, Sejong ^{[4
]}

Imm, Jee-Young ^{[1
]}

机构：

[1] Kookmin Univ, Dept Foods & Nutr, Seoul 136702, South Korea

[2] Korea Univ, Div Biotechnol, Seoul 136713, South Korea

[3] Korea Univ, Div Food Sci, Seoul 136713, South Korea

[4] Chonnam Natl Univ, Dept Anim Sci, Kwangju 500757, South Korea

来源：

INTERNATIONAL DAIRY JOURNAL | 2009年 / 19卷 / 11期

关键词：

WHEY-PROTEIN; CALCIUM BIOAVAILABILITY; PHOSPHATASE; PROLIFERATION; SUPPRESSES; RESORPTION; PEPTIDES; RELEASE; GROWTH; BOVINE;

D O I：

10.1016/j.idairyj.2009.06.009

中图分类号：

TS2 [食品工业];

学科分类号：

100403 [营养与食品卫生学];

摘要：

The effects of a Lactobacillus casei 393 fermented milk product (FMP) on bone metabolism were examined. FMP (>0.1 mg mL(-1)) supplementation significantly increased osteoblastic MC3T3-E1 cells proliferation whereas skim milk powder supplementation did not show any positive effect up to 1 mg mL(-1). The FMP (1%) supplemented ovariectomised rats had increased bone weight, bone mineral density, and bone breaking force compared with control ovariectomised rat. In addition, the activity of tartrate resistant acid phosphatase, a biomarker of osteoclasts, was significantly reduced in the FMP group. Based on the results, the L casei 393 FMP had a preventative effect on bone loss in ovariectomised rats. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：690 / 695

页数：6

共 32 条

[1]

[Anonymous], [No title captured]

[2]

[Anonymous], 1996, GUID CAR US LAB AN

[3]

Controlled trial of the effects of milk basic protein (MBP) supplementation on bone metabolism in healthy adult women [J].