Clobetasol ameliorates aphthous ulceration in renal transplant patients on sirolimus

被引：43

作者：

Chuang, P. ^{[1
]}

Langone, A. J. ^{[1
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Med, Div Nephrol & Hypertens, Nashville, TN 37232 USA

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2007年 / 7卷 / 03期

关键词：

aphthous ulceration; immunosuppressive therapy; Rapamycin; renal transplant; side effect; sirolimus; skin;

D O I：

10.1111/j.1600-6143.2006.01678.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Aphthous ulceration is a common side effect of sirolimus. These lesions of the oral mucous membranes are often painful and debilitating, leading to either dose reduction or discontinuation of sirolimus in a significant number of patients. We report that the direct application of clobetasol, a high potency topical steroid, led to prompt resolution of the aphthous ulcers that developed in our renal transplant patients on sir-olimus-based immunosuppression.

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收藏

页码：714 / 717

页数：4

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