The Learning Curve for the Laparoscopic Approach to Conservative Mesorectal Excision for Rectal Cancer Lessons Drawn From a Single Institution's Experience

被引:93
作者
Bege, Thierry
Lelong, Bernard [1 ]
Esterni, Benjamin [2 ]
Turrini, Olivier
Guiramand, Jerome
Francon, Daniel [3 ]
Mokart, Djamel [3 ]
Houvenaeghel, Gilles
Giovannini, Marc [4 ]
Delpero, Jean Robert
机构
[1] Inst J Paoli I Calmettes, Dept Surg Oncol, Reg Comprehens Canc Ctr, F-13009 Marseille, France
[2] Inst J Paoli I Calmettes, Dept Biostat, Reg Comprehens Canc Ctr, F-13009 Marseille, France
[3] Inst J Paoli I Calmettes, Dept Anesthesiol & Intens Care, Reg Comprehens Canc Ctr, F-13009 Marseille, France
[4] Inst J Paoli I Calmettes, Dept Digest Endoscopy, Reg Comprehens Canc Ctr, F-13009 Marseille, France
关键词
MRC CLASICC TRIAL; COLORECTAL SURGERY; RANDOMIZED-TRIAL; COLON-CANCER; RESECTION; CARCINOMA; OUTCOMES; COHORT; TME;
D O I
10.1097/SLA.0b013e3181b7fdb0
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objectives: We aimed to determine the most sensitive markers of the learning process for laparoscopic conservative mesorectal excision (LCME) for rectal cancer to (1) generate a relevant training program for junior surgeons and (2) define appropriate settings for prospective trials. Summary Background Data: The learning process for the laparoscopic approach to treating rectal cancer has not yet been clearly described. Methods: Over a 42-month period, 127 patients received LCME at Our institution. The procedure was performed or Supervised by a single referent surgeon. The operative time, conversion to open procedure postoperative morbidity, microscopic margins, and local recurrence were thought to be the most relevant parameters related to the learning process. To give a comprehensive view of success, a single hybrid variable was generated. Curves were drawn using the moving average method for continuous variables and the CUSUM analysis was used for binary variables. Results: A slow but continuous decrease in operative time was observed over all the study period. The overall and surgical morbidities were the most sensitive markers. The conversion rate and R0-resection rate remained stable at 14.9% and 91%, respectively. The overall local recurrence rate was 4.7% at a median follow-up time of 40 months and was not affected by the learning process. The success rate reached a steady state after 50 patients. Conclusion: Despite surgeons' early command of the conversion rate, the learning process for LCME affects morbidity for the first 50 patients operated on, but does not adversely affect the oncological results. Much emphasis should therefore be placed oil technical training.
引用
收藏
页码:249 / 253
页数:5
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