Stereoselective synthesis of 2 beta-carbomethoxy-3 beta-phenyltropane derivatives. Enhanced stereoselectivity observed for the conjugate addition reaction of phenylmagnesium bromide derivatives with anhydro dichloromethane

被引：23

作者：

Xu, LF

Trudell, ML

机构：

[1] Department of Chemistry, University of New Orleans, New Orleans

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 06期

关键词：

D O I：

10.1002/jhet.5570330676

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of dichloromethane as a solvent for the conjugate addition reaction of preformed etheral solutions of phenylmagnesium bromide derivatives with anhydroecgonine methyl ester (2) was found to enhance the stereoselectivity of the reaction and provide the 2 beta-carbomethoxy-3 beta-phenyltropane derivatives 3a-d in high yield.

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页码：2037 / 2039

页数：3

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