DNA analysis by mass spectrometry: Applications in DNA sequencing and DNA diagnostics

被引：9

作者：

Koster, H ^{[1
]}

vandenBoom, D ^{[1
]}

Braun, A ^{[1
]}

Jacob, A ^{[1
]}

Jurinke, C ^{[1
]}

Little, DP ^{[1
]}

Tang, K ^{[1
]}

机构：

[1] SEQUENOM INC,SAN DIEGO,CA 92121

来源：

NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 5-6期

关键词：

D O I：

10.1080/07328319708002917

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Use of mass spectrometry to detect PCR amplified DNA from individuals infected with hepatitis B virus, to derive DNA sequence information through exonuclease based degradation or Sanger sequencing and a new format (PROBE) for the efficient determination of mutations is described.

引用

收藏

页码：563 / 571

页数：9

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