Methotrexate-induced optic neuropathy

被引：11

作者：

Balachandran, C

McCluskey, PJ

Champion, GD

Halmagyi, GM

机构：

[1] Royal Prince Alfred Hosp, Dept Ophthalmol, Sydney, NSW, Australia

[2] Royal Prince Alfred Hosp, Inst Clin Neurosci, Sydney, NSW, Australia

[3] St Vincents Hosp, Dept Ophthalmol, Sydney, NSW 2010, Australia

[4] St Vincents Hosp, Dept Rheumatol, Sydney, NSW 2010, Australia

来源：

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | 2002年 / 30卷 / 06期

关键词：

methotrexate; optic neuropathy; rheumatoid arthritis; side-effect;

D O I：

10.1046/j.1442-9071.2002.00578.x

中图分类号：

R77 [眼科学];

学科分类号：

100212 [眼科学];

摘要：

A 53-year-old Caucasian woman with long-standing, well controlled, severe rheumatoid arthritis, treated with methotrexate, salazopyrin, naprosyn, prednisone and plaquenil, presented with progressive visual loss in each eye. She had a past history of non-necrotizing anterior scleritis that was treated with increased doses of prednisone. She developed left then right central scotomas, reduced vision and optic atrophy. Eventually a diagnosis of methotrexate-induced optic atrophy was made.

引用

页码：440 / 441

页数：2