Dendritic DNA Building Blocks for Amplified Detection Assays and Biomaterials

被引:33
作者
Feldkamp, Udo [1 ]
Sacca, Barbara [1 ]
Niemeyer, Christof M. [1 ]
机构
[1] TU Dortmund, Fak Chem Biol Chem Mikrostrukturtech, D-44227 Dortmund, Germany
关键词
dendrimers; DNA structures; gels; nanotechnology; proteins; DENDRIMERS;
D O I
10.1002/anie.200902285
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
DNA branches out: Recent advances in the assembly of dendritic DNA structures enable applications in biosensing of pathogens and the generation of novel pads of DNA hydrogel biomaterials (see scheme, left). These pads are immersed in a cell extract containing RNA polymerase (red), ribosomes (yellow), and other components for in vitro protein biosynthesis, where they can be used as templates for cell-free protein production. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:5996 / 6000
页数:5
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