Prognostic Factors in Idiopathic Pulmonary Fibrosis

被引：25

作者：

Tzilas, Vasilios ^{[1
]}

Koti, Aspasia ^{[1
]}

Papandrinopoulou, Dimitra ^{[1
]}

Tsoukalas, Georgios ^{[1
]}

机构：

[1] Athens Chest Dis Hosp Sotiria, Resp Med Dept 4, Athens, Greece

来源：

AMERICAN JOURNAL OF THE MEDICAL SCIENCES | 2009年 / 338卷 / 06期

关键词：

Idiopathic pulmonary fibrosis (IPF); Six-minute walk test (6MWT); Carbon monoxide diffusing capacity (DLco); Forced vital capacity (FVC); Six-minute walk distance (6MWD); USUAL INTERSTITIAL PNEUMONIA; FIBROBLASTIC FOCI; COMPUTED-TOMOGRAPHY; ACUTE EXACERBATION; 6-MINUTE WALK; CT FINDINGS; SURVIVAL; HYPERTENSION; LUNG; PROGRESSION;

D O I：

10.1097/MAJ.0b013e3181ad5984

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Idiopathic pulmonary fibrosis, 1 of the 7 idiopathic interstitial pneumonias, carries an ominous prognosis. It has a median survival of 2.8 years. However, there is significant heterogeneity in the actual length of survival, which varies from months to >5 years. Unfortunately, in addition to lung transplantation, no known medical intervention alters the natural history of the disease. Currently, many phase-Ill clinical trials are ongoing, but there is no Federal Drug Administration approved therapy. Thus, it is important for the clinician to be able to evaluate prognostic factors. These will help him draw conclusions about the possible course of his idiopathic pulmonary fibrosis patients and make important therapeutic decisions (lung transplantation).

引用

页码：481 / 485

页数：5

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