An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides

被引：859

作者：

Schafmeister, CE ^{[1
]}

Po, J ^{[1
]}

Verdine, GL ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2000年 / 122卷 / 24期

关键词：

D O I：

10.1021/ja000563a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：5891 / 5892

页数：2

共 13 条

[1] Forming stable helical peptides using natural and artificial amino acids [J].

Andrews, MJI ;

Tabor, AB .

TETRAHEDRON, 1999, 55 (40) :11711-11743

[2] A SALT BRIDGE STABILIZES THE HELIX FORMED BY ISOLATED C-PEPTIDE OF RNASE-A [J].

BIERZYNSKI, A ;

KIM, PS ;

BALDWIN, RL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (08) :2470-2474

[3]

Blackwell HE, 1998, ANGEW CHEM INT EDIT, V37, P3281, DOI 10.1002/(SICI)1521-3773(19981217)37:23<3281::AID-ANIE3281>3.0.CO

[4]

2-V

[5] SYNTHESIS AND NUCLEAR-MAGNETIC-RESONANCE STRUCTURE DETERMINATION OF AN ALPHA-HELICAL, BICYCLIC, LACTAM-BRIDGED HEXAPEPTIDE [J].

BRACKEN, C ;

GULYAS, J ;

TAYLOR, JW ;

BAUM, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (14) :6431-6432

[6] SUPRAMOLECULAR DESIGN BY COVALENT CAPTURE - DESIGN OF A PEPTIDE CYLINDER VIA HYDROGEN-BOND-PROMOTED INTERMOLECULAR OLEFIN METATHESIS [J].

CLARK, TD ;

GHADIRI, MR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (49) :12364-12365

[7]

GANTE J, 1994, ANGEW CHEM INT EDIT, V33, P1699, DOI 10.1002/anie.199416991

[8] COMPUTED CIRCULAR DICHROISM SPECTRA FOR EVALUATION OF PROTEIN CONFORMATION [J].

GREENFIE.N ;

FASMAN, GD .

BIOCHEMISTRY, 1969, 8 (10) :4108-&

[9] GENERAL-APPROACH TO THE SYNTHESIS OF SHORT ALPHA-HELICAL PEPTIDES [J].

JACKSON, DY ;

KING, DS ;

CHMIELEWSKI, J ;

SINGH, S ;

SCHULTZ, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (24) :9391-9392

[10] Stereochemical control of peptide folding [J].

Kaul, R ;

Balaram, P .

BIOORGANIC & MEDICINAL CHEMISTRY, 1999, 7 (01) :105-117

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