Catalytic, asymmetric synthesis of the C1′-C10′ segment of pamamycin 621A

被引:33
作者
Calter, MA [1 ]
Bi, FC [1 ]
机构
[1] Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA
关键词
D O I
10.1021/ol005714t
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] This paper describes a catalytic, asymmetric approach to the C-1'-C-10' segment of pamamycin 621A. We synthesize this segment in a convergent manner, with each of the coupling partners ultimately deriving from enantiomerically enriched methylketene dimer.
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收藏
页码:1529 / 1531
页数:3
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