Anti-platelet aggregation constituents from Gynura elliptica

被引：42

作者：

Lin, WY

Teng, CM

Tsai, IL

Chen, IS ^{[1
]}

机构：

[1] Kaohsiung Med Coll, Grad Inst Pharmaceut Sci, Kaohsiung, Taiwan

[2] Natl Taiwan Univ, Coll Med, Inst Pharmacol, Taipei, Taiwan

来源：

PHYTOCHEMISTRY | 2000年 / 53卷 / 08期

关键词：

Gynura elliptica; Compositae; root; p-hydroxyacetophenone; chromane; chroman-4-ol; (+)-gynunone; gynunol; anti-platelet aggregation activity;

D O I：

10.1016/S0031-9422(99)00599-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

A p-hydroxyacetophenone-like derivative, (+)-gynunone, and a chromane, together with six known compounds were isolated from the CNCl3 fraction of the roots of Gynura elliptica. Their structures were determined by means of spectral analyses. Among the isolates, 6-acetyl-2,2-dimethylchroman-4-one and vanillin showed anti-platelet aggregation activity induced by arachidonic acid in vitro. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：833 / 836

页数：4

共 21 条

[1]

PYRROLIZIDINE ALKALOIDS FROM CRASSOCEPHALUM-CREPIDIOIDES [J].