Recent patterns and predictors of antipsychotic medication regimens used to treat schizophrenia and other psychotic disorders

被引:75
作者
Wang, PS
West, JC
Tanielian, T
Pincus, HA
机构
[1] Harvard Univ, Sch Med, Boston, MA 02115 USA
[2] Amer Psychiat Inst Res & Educ, Amer Psychiat Practice Res Network, Washington, DC USA
[3] Amer Psychiat Assoc, Res Off, Washington, DC USA
[4] Univ Pittsburgh, Western Psychiat Inst & Clin, Dept Psychiat, Pittsburgh, PA 15213 USA
[5] RAND, Pittsburgh Hlth Program, Pittsburgh, PA USA
关键词
schizophrenia; psychotic disorders; antipsychotic medications; pharmacoepidemiology; psychiatrist prescribing patterns;
D O I
10.1093/oxfordjournals.schbul.a033465
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Up-to date data are needed on the types of treatments used by psychiatrists and the reasons for use of particular treatments. Using 1997 American Psychiatric Association (APA) Practice Research Network (PRN) Study data on patients with schizophrenia and other psychotic disorders, me identified the characteristics of antipsychotic medications (APMs) currently being prescribed and factors associated with the use of particular regimens, In this study population, use of the newer APMs, including risperidone, olanzapine, and clozapine, has increased rapidly and now accounts for over one-half of all APM use, Other intriguing findings include the fact that one-sixth of patients with schizophrenia and other psychotic disorders are concurrently treated with two or more APMs, Factors associated with being prescribed one of the newer APMs risperidone or olanzapine include being elderly, having more education, being white, having psychiatric comorbidity, and making fewer recent visits to a psychiatrist. The APA PRN Study data are an important new resource for mental health services researchers.
引用
收藏
页码:451 / 457
页数:7
相关论文
共 11 条
[1]   CLINICAL SERVICES RESEARCH [J].
ATTKISSON, C ;
COOK, J ;
KARNO, M ;
LEHMAN, A ;
MCGLASHAN, TH ;
MELTZER, HY ;
OCONNOR, M ;
RICHARDSON, D ;
ROSENBLATT, A ;
WELLS, K ;
WILLIAMS, J ;
HOHMANN, AA .
SCHIZOPHRENIA BULLETIN, 1992, 18 (04) :561-626
[2]  
*DEP HLTH HUM SERV, 1992, REP FED TASK FORC HO
[3]  
FRANCES A, 1996, J CLIN PSYCHIAT S12B, V57, P1
[4]  
Herz MI, 1997, AM J PSYCHIAT, V154, P1
[5]  
Lehman AF, 1998, SCHIZOPHRENIA BULL, V24, P1
[6]   Treatment outcomes in schizophrenia: Implications for practice, policy, and research [J].
Lehman, AF ;
Carpenter, WT ;
Goldman, HH ;
Steinwachs, DM .
SCHIZOPHRENIA BULLETIN, 1995, 21 (04) :669-675
[7]  
Lehman AF, 1996, J CLIN PSYCHIAT, V57, P61
[8]   A SELECTIVE REVIEW OF RECENT NORTH-AMERICAN LONG-TERM FOLLOW-UP STUDIES OF SCHIZOPHRENIA [J].
MCGLASHAN, TH .
SCHIZOPHRENIA BULLETIN, 1988, 14 (04) :515-542
[9]   Psychiatric patients and treatments in 1997 - Findings from the American Psychiatric Practice Research Network [J].
Pincus, HA ;
Zarin, DA ;
Tanielian, TL ;
Johnson, JL ;
West, JC ;
Pettit, AR ;
Marcus, SC ;
Kessler, RC ;
McIntyre, JS .
ARCHIVES OF GENERAL PSYCHIATRY, 1999, 56 (05) :441-449
[10]  
Zarin DA, 1997, AM J PSYCHIAT, V154, P1199