Quantitative genetic analyses of complex behaviours in Drosophila

被引：114

作者：

Anholt, RRH ^{[1
]}

Mackay, TFC

机构：

[1] N Carolina State Univ, Dept Zool, Raleigh, NC 27695 USA

[2] N Carolina State Univ, Dept Genet, Raleigh, NC 27695 USA

[3] N Carolina State Univ, WM Keck Ctr Behav Biol, Raleigh, NC 27695 USA

来源：

NATURE REVIEWS GENETICS | 2004年 / 5卷 / 11期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrg1472

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学]; 090102 [作物遗传育种];

摘要：

Behaviours are exceptionally complex quantitative traits. Sensitivity to environmental variation and genetic background, the presence of sexual dimorphism, and the widespread functional pleiotropy that is inherent in behavioural phenotypes pose daunting challenges for unravelling their underlying genetics. Drosophila melanogaster provides an attractive system for elucidating the unifying principles of the genetic architectures that drive behaviours, as genetically identical individuals can be reared rapidly in controlled environments and extensive publicly accessible genetic resources are available. Recent advances in quantitative genetic and functional genomic approaches now enable the extensive characterization of complex genetic networks that mediate behaviours in this important model organism.

引用

页码：838 / 849

页数：12

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