Clinical Evaluation of a (1,3)-β-D-Glucan Assay for Presumptive Diagnosis of Pneumocystis jiroveci Pneumonia in Immunocompromised Patients

被引：20

作者：

Del Bono, Valerio ^{[1
]}

Mularoni, Alessandra ^{[1
]}

Furfaro, Elisa ^{[1
]}

Delfino, Emanuele ^{[1
]}

Rosasco, Lorenzo ^{[2
]}

Miletich, Franca ^{[1
]}

Viscoli, Claudio ^{[1
]}

机构：

[1] Univ San Martino, Clin Malattie Infett, Azienda Osped, I-16132 Genoa, Italy

[2] Univ Genoa, DISI, Genoa, Italy

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2009年 / 16卷 / 10期

关键词：

INVASIVE FUNGAL-INFECTIONS; BETA-D-GLUCAN; REACTIVITY; LEUKEMIA; SERUM;

D O I：

10.1128/CVI.00276-09

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

(1,3)-beta-D-Glucan (BG) is a component of the Pneumocystis jiroveci cell wall. Thirty-one immunocompromised patients with pneumonia (16 with presumptive pneumocystis pneumonia [PCP] and 15 with non-PCP) were evaluated for serum BG levels. Serum from all 16 presumptive PCP patients and from 2/15 patients with non-PCP was positive for BG. Results indicate that BG is a reliable marker for diagnosing PCP.

引用

页码：1524 / 1526

页数：3

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