Current perspectives in dissolution testing of conventional and novel dosage forms

被引：207

作者：

Azarmi, Shirzad

Roa, Wilson

Lobenberg, Raimar ^{[1
]}

机构：

[1] Univ Alberta, Fac Pharm & Pharmaceut Sci, Edmonton, AB T6J 2L7, Canada

[2] Tabriz Univ Med Sci, Fac Pharm, Pharmaceut Nanotechnol Res Ctr, Tabriz, Iran

[3] Univ Alberta, Cross Canc Inst, Dept Radiat Oncol, Edmonton, AB T6J 2L7, Canada

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2007年 / 328卷 / 01期

关键词：

dissolution testing; USP; novel dosage forms; conventional dosage forms; immediate-release tablets; powders; extended-release; chewable tablets; buccal/sublingual tablets; chewing gums; soft gelatin capsules; suppositories; transdermal patches; semisolids; aerosols;

D O I：

10.1016/j.ijpharm.2006.10.001

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The purpose of this article is to review USP and non-pharmacopcial dissolution testing methods for conventional and novel pharmaceutical dosage forms and give an insight to possible alternatives in drug dissolution study design and appropriate choices for dissolution media. For each dosage form first the USP method(s) for dissolution testing are reviewed followed by alternative methods used in research and development. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：12 / 21

页数：10

共 84 条

[1] Determination of the in vitro disintegration profile of rapidly disintegrating tablets and correlation with oral disintegration [J].