Sensitivity analysis of a nanowire-based surface plasmon resonance biosensor in the presence of surface roughness

被引:33
作者
Byun, Kyung Min
Yoon, Soon Joon
Kim, Donghyun [1 ]
Kim, Sung June
机构
[1] Yonsei Univ, Sch Elect & Elect Engn, Seoul 120749, South Korea
[2] Seoul Natl Univ, Sch Elect Engn & Comp Sci, Seoul 151742, South Korea
[3] Seoul Natl Univ, Nano Bioelect & Syst Res Ctr, Seoul 151742, South Korea
关键词
D O I
10.1364/JOSAA.24.000522
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We have investigated the effect of surface roughness on the sensitivity of conventional and nanowire-based surface plasmon resonance (SPR) biosensors. The theoretical research was conducted using rigorous coupled-wave analysis with Gaussian surface profiles of gold films determined by atomic force microscopy. The results suggest that, when surface roughness ranges near 1 run, the sensitivity of a conventional SPR system is not significantly affected regardless of the correlation length. For a nanowire-based SPR biosensor, however, we have found that the sensitivity degrades substantially with decreasing correlation length. In particular, at a correlation length smaller than 100 nm, a random rough surface may induce destructive coupling between excited localized surface plasmons, which can lead to prominent reduction of sensitivity enhancement. (c) 2007 Optical Society of America
引用
收藏
页码:522 / 529
页数:8
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