Switching gears during T-cell maturation: RANTES and late transcription

被引：53

作者：

Ortiz, BD

Nelson, PJ

Krensky, AM

机构：

[1] UNIV MUNICH, CLIN INNENSTADT, CLIN BIOCHEM GRP, DEPT INTERNAL MED, D-80336 MUNICH, GERMANY

[2] STANFORD UNIV, SCH MED, DEPT PEDIAT, STANFORD, CA 94305 USA

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 10期

关键词：

D O I：

10.1016/S0167-5699(97)01128-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Although much is understood about the induction of genes expressed early (within 24 h) after T-cell activation, little is known about the regulation of expression of genes expressed 'late' (three or more days) post-stimulation. A better understanding of transcriptional regulation at this important stage of T-cell maturation may yield new insights into T-cell development and new immunotherapeutic targets.

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收藏

页码：468 / 471

页数：4

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