Articular cartilage chondrons: Form, function and failure

被引：309

作者：

Poole, CA ^{[1
]}

机构：

[1] UNIV MANCHESTER,SCH BIOL SCI,WELLCOME TRUST CTR CELL MATRIX RES,MANCHESTER M13 9PL,LANCS,ENGLAND

来源：

JOURNAL OF ANATOMY | 1997年 / 191卷

关键词：

articular cartilage; chondrons; chondrocytes; pericellular microenvironment; osteoarthritis;

D O I：

10.1046/j.1469-7580.1997.19110001.x

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The chondrocyte and its pericellular microenvironment together represent the chondron, historically considered the primary structural, functional and metabolic unit of articular and other hyaline cartilages. This review summarises research over the last 10 years to establish the molecular anatomy, functional properties and metabolic contribution of the chondron in articular cartilage homeostasis, and its failure during the initiation and progression of degenerative osteoarthritis.

引用

页码：1 / 13

页数：13

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