Neural substrates of memory: From synapse to system

被引:75
作者
Dubnau, J
Chiang, AS
Tully, T
机构
[1] Cold Spring Harbor Labs, Cold Spring Harbor, NY 11724 USA
[2] Natl Tsing Hua Univ, Dept Life Sci, Hsinchu 30043, Taiwan
来源
JOURNAL OF NEUROBIOLOGY | 2003年 / 54卷 / 01期
关键词
neural substrates; memory; theoretical modeling; behavioral analyses;
D O I
10.1002/neu.10170
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
One of the fundamental challenges of modern neuroscience is to understand how memories are acquired, stored, and retrieved by the brain. In the broadest terms, attempts to dissect memory can be broken down into four experimental disciplines: (1) identification of molecular components, (2) ex vivo and in vivo cellular analysis of neuronal function, (3) theoretical modeling approaches of neural systems, and (4) organismal-level behavioral analyses. Our objective here is to offer a conceptually unifying perspective and to discuss this perspective in relation to an experiment analysis of memory in Drosophila. (C) 2003 Wiley Periodicals, Inc.
引用
收藏
页码:238 / 253
页数:16
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