Zinc-mediated acylation and sulfonation of pyrrole and its derivatives

被引：35

作者：

Yadav, JS ^{[1
]}

Reddy, BVS ^{[1
]}

Kondaji, G ^{[1
]}

Rao, RS ^{[1
]}

Kumar, SP ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 45期

关键词：

organozinc reagents; C-acylation; sulfonylation; pyrrole; 2-substituted pyrrole;

D O I：

10.1016/S0040-4039(02)01914-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrrole and its derivatives react smoothly with acid chlorides and sulfonyl chlorides in the presence of zinc metal in toluene at ambient temperature to afford the corresponding 2-acetyl and 2-sulfonyl pyrrole derivatives in high yields with high regioselectivity. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：8133 / 8135

页数：3

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