Protection of DNA and microsomal membranes in vitro by Glycyrrhiza glabra L. against gamma irradiation

被引:28
作者
Shetty, TK [1 ]
Satav, JG [1 ]
Nair, CKK [1 ]
机构
[1] Bhabha Atom Res Ctr, Div Radiat Biol, Bombay 400085, Maharashtra, India
关键词
G. glabra L; gamma radiation; microsomal lipid peroxidation; plasmid DNA;
D O I
10.1002/ptr.927
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The radioprotective effect of the root extract of Glycyrrhiza glabra L on lipid peroxidation in rat liver microsomes and plasmid pBR322 DNA was investigated. The extract was found to protect microsomal membranes, as evident from reduction in lipid peroxidation, and could also protect plasmid DNA from radiation-induced strand breaks. Copyright (C) 2002 John Wiley Sons, Ltd.
引用
收藏
页码:576 / 578
页数:3
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