Prenatal alcohol exposure: Advancing knowledge through international collaborations

被引:29
作者
Riley, EP
Guerri, C
Calhoun, F
Charness, ME
Foroud, TM
Li, TK
Mattson, SN
May, PA
Warren, KR
机构
[1] San Diego State Univ, Ctr Behav Teratol, San Diego, CA 92120 USA
[2] Inst Invest Citological Caja Ahorros Valencia, Valencia, Spain
[3] NIAAA, Bethesda, MD USA
[4] Harvard Univ, Sch Med, Boston, MA 02115 USA
[5] Indiana Univ, Sch Med, Indianapolis, IN 46204 USA
[6] Univ New Mexico, Albuquerque, NM 87131 USA
关键词
FAS; international studies; review;
D O I
10.1097/01.ALC.0000047351.03586.A3
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Fetal alcohol syndrome (FAS) is a major public health issue that is evident on an international scale. The current article summarizes a meeting that was held in Valencia, Spain, in September 2001, that reviewed ongoing international collaborations and the prospects for new collaborative research. The attendees represented nine different countries and many different specialties. Following overviews of existing international collaborations in South Africa, Russia, and Chile, a number of topics for future work were discussed. Issues related to the diagnosis of FAS, its prevalence and how measures might be enhanced and standardized were presented, as obtaining consistency across populations is of prime importance. Another session discussed the current state of basic research and how collaborations in this area might be initiated. The neurobehavioral profile of FAS and how work in this area could be advanced and interpreted in light of findings with different populations generated considerable discussion. There was a review of brain imaging data in FAS and how this might be utilized in assisting the diagnosis of FAS and alcohol-related neurodevelopmental disorder (ARND). A presentation on the utilization of international collaborations in defining the role of genetics in the etiology of FAS was included. Finally, issues related to the prevention of FAS and how these issues might be modified based upon different populations were presented. International collaborations provide a wealth of resources for the study of FAS, and it was hoped that this meeting might better enhance the work ongoing in this area, and provide opportunities for future work.
引用
收藏
页码:118 / 135
页数:18
相关论文
共 50 条
[1]  
Abel E. L., 1990, FETAL ALCOHOL SYNDRO
[2]   Patterns of cognitive-motor development in children with fetal alcohol syndrome from a community in South Africa [J].
Adnams, CM ;
Kodituwakku, PW ;
Hay, A ;
Molteno, CD ;
Viljoen, D ;
May, PA .
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2001, 25 (04) :557-562
[3]   Brain dysmorphology in individuals with severe prenatal alcohol exposure [J].
Archibald, SL ;
Fennema-Notestine, C ;
Gamst, A ;
Riley, EP ;
Mattson, SN ;
Jernigan, TL .
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2001, 43 (03) :148-154
[4]  
CHARNESS ME, 1994, J BIOL CHEM, V269, P9304
[5]   Octanol antagonism of ethanol teratogenesis [J].
Chen, SY ;
Wilkemeyer, MF ;
Sulik, KK ;
Charness, ME .
FASEB JOURNAL, 2001, 15 (07) :1649-+
[6]   Ethanol exposure enhances cell death in the developing cerebral cortex: Role of brain-derived neurotrophic factor and its signaling pathways [J].
Climent, E ;
Pascual, M ;
Renau-Piqueras, J ;
Guerri, C .
JOURNAL OF NEUROSCIENCE RESEARCH, 2002, 68 (02) :213-225
[7]   GENE DOSE OF APOLIPOPROTEIN-E TYPE-4 ALLELE AND THE RISK OF ALZHEIMERS-DISEASE IN LATE-ONSET FAMILIES [J].
CORDER, EH ;
SAUNDERS, AM ;
STRITTMATTER, WJ ;
SCHMECHEL, DE ;
GASKELL, PC ;
SMALL, GW ;
ROSES, AD ;
HAINES, JL ;
PERICAKVANCE, MA .
SCIENCE, 1993, 261 (5123) :921-923
[8]  
Cudd TA, 2002, ALCOHOL CLIN EXP RES, V26, P53
[9]   Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome [J].
Deltour, L ;
Ang, HL ;
Duester, G .
FASEB JOURNAL, 1996, 10 (09) :1050-1057
[10]   Cellular and molecular neuroscience of alcoholism [J].
Diamond, I ;
Gordon, AS .
PHYSIOLOGICAL REVIEWS, 1997, 77 (01) :1-20