The Utility of Repeated Stool Toxin Testing for Diagnosing Clostridium difficile Colitis

被引：6

作者：

Gade, Rajesh ^{[1
]}

Turett, Glenn ^{[1
]}

机构：

[1] St Vincent Catholic Med Ctr, Dept Infect Dis, New York, NY 10011 USA

来源：

SOUTHERN MEDICAL JOURNAL | 2009年 / 102卷 / 10期

关键词：

Clostridium difficile; enzyme-linked immunoassay; pseudomembranous colitis; sensitivity and specificity; DIARRHEA; VIRUS;

D O I：

10.1097/SMJ.0b013e3181b08c42

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clostridium difficile is diagnosed using the enzyme-linked immunoassay (EIA) with the specificity and sensitivity ranging from 50-90% and 70-95%, respectively. Due to the wide ranges, there is considerable confusion regarding the value of the EIA toxin test. We undertook this study to evaluate the benefit of repeat stool toxin testing.

引用

页码：1007 / 1009

页数：3

共 12 条

[1] CLOSTRIDIUM-DIFFICILE - CLINICAL CONSIDERATIONS [J].

BARTLETT, JG .

REVIEWS OF INFECTIOUS DISEASES, 1990, 12 :S243-S251

[2] ANTIBIOTIC-ASSOCIATED PSEUDOMEMBRANOUS COLITIS DUE TO TOXIN-PRODUCING CLOSTRIDIA [J].

BARTLETT, JG ;

CHANG, TW ;

GURWITH, M ;

GORBACH, SL ;

ONDERDONK, AB .

NEW ENGLAND JOURNAL OF MEDICINE, 1978, 298 (10) :531-534

[3]

BROWN E, 1990, INFECT CONT HOSP EP, V11, P283

[4]

GRONCZEWSKI C, CLOSTRIDIUM DIFFUCIL

[5] EVALUATION OF A RAPID ENZYME-LINKED IMMUNOASSAY FOR THE DIAGNOSIS OF HERPES-SIMPLEX VIRUS IN CANCER-PATIENTS WITH ORAL LESIONS [J].

LAGA, EA ;

TOTH, BB ;

ROLSTON, KV ;

TARRAND, JJ .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1993, 75 (02) :168-172

[6] CLOSTRIDIUM DIFICILE COLITIS - AN EFFICIENT CLINICAL APPROACH TO DIAGNOSIS [J].

MANABE, YC ;

VINETZ, JM ;

MOORE, RD ;

MERZ, C ;

CHARACHE, P ;

BARTLETT, JG .

ANNALS OF INTERNAL MEDICINE, 1995, 123 (11) :835-+

[7]

Miller MA, 1998, INFECT CONT HOSP EP, V19, P691

[8] Lack of value of repeat stool testing for Clostridium difficile toxin [J].

Mohan, SS ;

McDermott, BP ;

Parchuri, S ;

Cunha, BA .

AMERICAN JOURNAL OF MEDICINE, 2006, 119 (04) :356.e7-356.e8

[9]

Renshaw AA, 1996, ARCH PATHOL LAB MED, V120, P49

[10] Clostridium difficile associated diarrhoea:: diagnosis and treatment [J].

Starr, J .

BMJ-BRITISH MEDICAL JOURNAL, 2005, 331 (7515) :498-501

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