Optimizing therapy of seizures in adult patients with psychiatric comorbidity

被引：33

作者：

Brodtkorb, Eylert ^{[1
]}

Mula, Marco

机构：

[1] Univ Trondheim Hosp, St Olavs Hosp, Dept Neurol & Clin Neurophysiol, N-7006 Trondheim, Norway

[2] Univ Trondheim Hosp, Trondheim, Norway

[3] Norwegian Univ Sci & Technol, Fac Med, Dept Neurosci, N-7034 Trondheim, Norway

[4] Amedeo Avogadro Univ, Dept Neurol, Novara, Italy

[5] Univ Pisa, Dept Psychiat Neurobiol Pharmacol & Biotechnol, I-56100 Pisa, Italy

来源：

NEUROLOGY | 2006年 / 67卷 / 12期

关键词：

D O I：

10.1212/WNL.67.12_suppl_4.S39

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This article provides an overview of appropriate antiepileptic treatment in adult patients with chronic epilepsy and concomitant psychiatric disorders. It highlights the influence of various treatment options for epilepsy on psychiatric symptoms. Six specific topics are discussed: psychosocial aspects and treatment compliance; positive and negative psychotropic effects of antiepileptic drugs (AEDs); pharmacokinetic and pharmacodynamic interactions between AEDs and psychoactive drugs; risks and benefits of resective surgery; the effect of vagal nerve stimulation; and recommended strategies for optimizing epilepsy therapy in patients with psychiatric disorders. Given the multitude of epilepsy treatment options with various CNS effects, it is crucial to select treatments according to the clinical profile of each individual patient.

引用

页码：S39 / S44

页数：6

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