The human olfactory mucosa

被引：76

作者：

Escada, Pedro Alberto ^{[1
]}

Lima, Carlos ^{[2
]}

da Silva, Jose Madeira ^{[1
]}

机构：

[1] Univ Nova Lisboa, Serv Otorrinolaringol, Fac Ciencias Med, Hosp Egas Moniz,Ctr Hosp Lisboa Ocidental, P-1349019 Lisbon, Portugal

[2] Univ Nova Lisboa, Serv Neurol & Neuropatol, Hosp Egas Moniz, Ctr Hosp Lisboa Ocidental, P-1349019 Lisbon, Portugal

来源：

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | 2009年 / 266卷 / 11期

关键词：

Biopsy; Humans; Nasal cavity; Nerve regeneration; Nervous system diseases; Olfactory mucosa; SPINAL-CORD-INJURY; ENSHEATHING CELL TRANSPLANTATION; GLOBOSE BASAL-CELLS; HUMAN NASAL-MUCOSA; RECEPTOR NEURONS; SENSORY NEURONS; ALZHEIMERS-DISEASE; STEM-CELLS; EPITHELIUM; BIOPSY;

D O I：

10.1007/s00405-009-1073-x

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 [耳鼻咽喉科学];

摘要：

Studies of the tissues of the human olfactory mucosa have been performed to investigate olfactory dysfunction and, more recently, olfactory mucosa has attracted a novel interest of investigators because it can be used as an early marker of neurodegenerative conditions of the brain and as a source of multipotent neural stem cells, with applications in regenerative medicine. The olfactory mucosa is readily available to the otolaryngologist, but the harvesting of this tissue must be safe, effective, and reliable, obtaining as little tissue as necessary, while avoiding unnecessary harm to the remaining olfactory tissue and function. The purpose of this review is to summarize the results of the most important studies and knowledge with regard to the human olfactory mucosa and its applications, emphasizing the issue of the distribution of the olfactory mucosa in the nasal cavities.

引用

页码：1675 / 1680

页数：6

共 88 条

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