Tamoxifen: the drug that came in from the cold

被引：31

作者：

Hughes-Davies, L. ^{[1
]}

Caldas, C. ^{[2
,3
,4
]}

Wishart, G. C. ^{[1
,4
]}

机构：

[1] Addenbrookes Hosp, Cambridge Breast Unit, Cambridge CB2 2QQ, England

[2] Univ Cambridge, Dept Oncol, Cambridge CB2 0RE, England

[3] Li Ka Shing Ctr, Funct Breast Canc Genom Lab, Canc Res UK Cambridge Res Inst, Cambridge CB2 0RE, England

[4] NIHR Cambridge Biomed Res Ctr, Cambridge, England

来源：

BRITISH JOURNAL OF CANCER | 2009年 / 101卷 / 06期

关键词：

breast cancer; adjuvant therapy; tamoxifen; aromatase inhibitors; oestrogen receptor; post-menopausal; EXTENDED ADJUVANT THERAPY; EARLY BREAST-CANCER; TO-TREAT ANALYSIS; POSTMENOPAUSAL WOMEN; ANASTROZOLE; LETROZOLE; TRIAL;

D O I：

10.1038/sj.bjc.6605231

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Despite the perception of many oncologists that tamoxifen is an inferior drug, and should be substituted by an aromatase inhibitor in post-menopausal women, the current evidence strongly supports the view that AIs should be used 2-3 years after tamoxifen to achieve the maximal overall survival ( OS) advantage. British Journal of Cancer ( 2009) 101, 875-878. doi:10.1038/sj.bjc.6605231 www.bjcancer.com Published online 11 August 2009 (C) 2009 Cancer Research UK

引用

页码：875 / 878

页数：4

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