Nucleotide sequence of equine MxA cDNA

被引：8

作者：

Chesters, PM ^{[1
]}

Steele, M ^{[1
]}

Purewal, A ^{[1
]}

Edington, N ^{[1
]}

机构：

[1] UNIV LONDON ROYAL VET COLL,DEPT PATHOL & INFECT DIS,LONDON NW1 0TU,ENGLAND

来源：

DNA SEQUENCE | 1997年 / 7卷 / 3-4期

关键词：

cDNA sequence; equine Mx; Mx protein;

D O I：

10.3109/10425179709034043

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A 2.6 kb cDNA species has been isolated from a cDNA library prepared from interferon-alpha stimulated equine peripheral blood leucocytes and the nucleotide sequence determined. The cDNA has a single open reading frame potentially encoding a 660 amino acid polypeptide showing a high degree of homology with known mammalian Mr proteins, including the possession of three consensus GTP-binding motifs. The protein has a calculated pI = 6.1 and in accordance with proposed nomenclature we have designated it equine MxA.

引用

页码：239 / 242

页数：4

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