A new functional suppressor tRNA/aminoacyl-tRNA synthetase pair for the in vivo incorporation of unnatural amino acids into proteins

被引：123

作者：

Wang, L ^{[1
]}

Magliery, TJ ^{[1
]}

Liu, DR ^{[1
]}

Schultz, PG ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2000年 / 122卷 / 20期

关键词：

D O I：

10.1021/ja000595y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：5010 / 5011

页数：2

共 14 条

[1] PROBING PROTEIN-STRUCTURE AND FUNCTION WITH AN EXPANDED GENETIC-CODE [J].

CORNISH, VW ;

MENDEL, D ;

SCHULTZ, PG .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1995, 34 (06) :621-633

[2] Universal rules and idiosyncratic features in tRNA identity [J].

Giegé, R ;

Sissler, M ;

Florentz, C .

NUCLEIC ACIDS RESEARCH, 1998, 26 (22) :5017-5035

[3] CONVERSION OF AMINOACYLATION SPECIFICITY FROM TRANSFER RNA(TYR) TO TRANSFER RNA(SER) INVITRO [J].

HIMENO, H ;

HASEGAWA, T ;

UEDA, T ;

WATANABE, K ;

SHIMIZU, M .

NUCLEIC ACIDS RESEARCH, 1990, 18 (23) :6815-6819

[4] Human tyrosyl tRNA synthetase shares amino acid sequence homology with a putative cytokine [J].

Kleeman, TA ;

Wei, DB ;

Simpson, KL ;

First, EA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (22) :14420-14425

[5] MUTANTS OF ESCHERICHIA-COLI INITIATOR TRANSFER-RNA THAT SUPPRESS AMBER CODONS IN SACCHAROMYCES-CEREVISIAE AND ARE AMINOACYLATED WITH TYROSINE BY YEAST EXTRACTS [J].

LEE, CP ;

RAJBHANDARY, UL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (24) :11378-11382

[6] Progress toward the evolution of an organism with an expanded genetic code [J].

Liu, DR ;

Schultz, PG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (09) :4780-4785

[7] Engineering a tRNA and aminoacyl-tRNA synthetase for the site-specific incorporation of unnatural amino acids into proteins in vivo [J].

Liu, DR ;

Magliery, TJ ;

Pasternak, M ;

Schultz, PG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (19) :10092-10097

[8] Co-expression of yeast amber suppressor tRNATyr and tyrosyl-tRNA synthetase in Escherichia coli:: Possibility to expand the genetic code [J].

Ohno, S ;

Yokogawa, T ;

Fujii, I ;

Asahara, H ;

Inokuchi, H ;

Nishikawa, K .

JOURNAL OF BIOCHEMISTRY, 1998, 124 (06) :1065-1068

[9] SPECIES-SPECIFIC MICROHELIX AMINOACYLATION BY A EUKARYOTIC PATHOGEN TRANSFER-RNA SYNTHETASE DEPENDENT ON A SINGLE-BASE PAIR [J].

QUINN, CL ;

TAO, NJ ;

SCHIMMEL, P .

BIOCHEMISTRY, 1995, 34 (39) :12489-12495

[10] AN OPERATIONAL RNA CODE FOR AMINO-ACIDS AND POSSIBLE RELATIONSHIP TO GENETIC-CODE [J].

SCHIMMEL, P ;

GIEGE, R ;

MORAS, D ;

YOKOYAMA, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (19) :8763-8768

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