Liquid-liquid immiscibility in lipid monolayers

被引:45
作者
Hagen, JP [1 ]
McConnell, HM [1 ]
机构
[1] STANFORD UNIV,DEPT CHEM,STANFORD,CA 94305
来源
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1997年 / 1329卷 / 01期
基金
美国国家科学基金会;
关键词
phase diagrams; fluorescence microscopy; critical point;
D O I
10.1016/S0005-2736(97)00135-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Some binary lipid mixtures form coexisting liquid phases when spread at the air/water interface. This work describes the pressure-composition phase diagrams of binary mixtures of four unsaturated phosphatidylcholines with dihydrocholesterol. These four binary mixtures have critical compositions of approximately fifty mole percent, and average critical exponents of 0.25 +/- 0.07. The data can also be approximated by a regular solution thermodynamic model, yielding parameters for the non-ideality of these mixtures. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:7 / 11
页数:5
相关论文
共 14 条
  • [1] DATTA DB, 1987, MEMBRANE BIOCHEM, P72
  • [2] Critical pressures in multicomponent lipid monolayers
    Hagen, JP
    McConnell, HM
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1996, 1280 (02): : 169 - 172
  • [3] HIRCHFELD CL, 1990, J PHYS FR, V51, P1537
  • [4] THEORY OF SUPERSTRUCTURES IN LIPID MONOLAYER PHASE-TRANSITIONS
    KELLER, DJ
    MCCONNELL, HM
    MOY, VT
    [J]. JOURNAL OF PHYSICAL CHEMISTRY, 1986, 90 (11) : 2311 - 2315
  • [5] KIRKWOOD JG, 1961, CHEM THERMODYN, pCH11
  • [6] SEEING PHENOMENA IN FLATLAND - STUDIES OF MONOLAYERS BY FLUORESCENCE MICROSCOPY
    KNOBLER, CM
    [J]. SCIENCE, 1990, 249 (4971) : 870 - 874
  • [7] LEE KYC, 1995, BIOPHYS J, V8, P1740
  • [8] MCCONNELL HM, 1991, ANNU REV PHYS CHEM, V42, P171, DOI 10.1146/annurev.pc.42.100191.001131
  • [9] PHOSPHOLIPID AND PHOSPHOLIPID-PROTEIN MONOLAYERS AT THE AIR/WATER INTERFACE
    MOHWALD, H
    [J]. ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 1990, 41 : 441 - 476
  • [10] PHILLIPS MC, 1972, PROGR SURFACE MEMBRA, V5