Lifetime of plasma cells in the bone marrow

被引:676
作者
Manz, RA [1 ]
Thiel, A [1 ]
Radbruch, A [1 ]
机构
[1] DEUTSCH RHEUMAFORSCHUNGSZENTRUM BERLIN,D-10115 BERLIN,GERMANY
关键词
D O I
10.1038/40540
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Immune protection is based on long-lived memory cells and effector cells, which are either cytotoxic or secrete antibodies. The lifespan of these effector cells has not so far been determined. Here we show that antibody-secreting plasma cells from bone marrow are as long-lived as memory B cells.
引用
收藏
页码:133 / 134
页数:2
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