Relationship Between Carotid Intima-Media Thickness and Silent Cerebral Infarction in Japanese Subjects With Type 2 Diabetes

被引：60

作者：

Nomura, Kazuhiro ^{[1
]}

Hamamoto, Yoshiyuki ^{[2
]}

Takahara, Shiho ^{[2
]}

Kikuchi, Osamu ^{[1
]}

Honjo, Sachiko ^{[1
]}

Ikeda, Hiroki ^{[1
]}

Wada, Yoshiharu ^{[1
]}

Nabe, Koichro ^{[1
]}

Okumra, Ryosuke ^{[3
]}

Koshiyama, Hiroyuki ^{[1
]}

机构：

[1] Kitano Hosp, Tazuke Kofukai Med Res Inst, Ctr Diabet & Endocrinol, Osaka, Japan

[2] Kyoto Univ, Dept Diabet & Clin Nutr, Grad Sch Med, Kyoto, Japan

[3] Kitano Hosp, Tazuke Kofukai Med Res Inst, Dept Radiol, Osaka, Japan

来源：

DIABETES CARE | 2010年 / 33卷 / 01期

关键词：

ARTERIAL-WALL THICKNESS; PULSE-WAVE VELOCITY; BASAL GANGLIA; RISK-FACTORS; STROKE; LESIONS;

D O I：

10.2337/dc09-0453

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

OBJECTIVE - We examined the relationship between intima-media thickness of common carotid artery (CCA-IMT) and silent cerebral infarction (SCI) with the magnetic resonance imaging (MRI) study in Japanese subjects with type 2 diabetes. RESEARCH DESIGN AND METHODS - The brain MRI study and the carotid ultrasonography were performed in a total of 217 consecutive Japanese subjects with type 2 diabetes. Various risk factors for SCI were examined using multiple logistic analyses. RESULTS - The SCI was found in 60.4% of the diabetic subjects. in the diabetic subjects, age, Systolic blood pressure (SBP), pulse wave velocity, and CCA-IMT were significantly higher in the subjects With SCI than in those without it. Multiple logistic analyses indicated that age, SBP, and CCA-IMT were significant and independent risk factors of SCI in the diabetic subjects. CONCLUSIONS - CCA-IMT, but not pulse wave velocity, was independently associated with SCI in Japanese subjects with type 2 diabetes.

引用

页码：168 / 170

页数：3

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